X-Ray induced DNA damage – why use plants?
نویسندگان
چکیده
منابع مشابه
Evaluating Gamma-H2AX Expression as a Biomarker of DNA Damage after X-ray in Angiography Patients
Objective: Coronary heart disease (CHD) is one of the most common diseases. Coronary angiography (CAG) is an important apparatus used to diagnose and treat this disease. Since angiography is performed through exposure to ionizing radiation, it can cause harmful effects induced by double-stranded breaks in DNA which is potentially life-threatening damage. The aim of the present study is to inves...
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In this work, the chemical changes in calf thymus DNA samples were analyzed by X-ray photoelectron spectroscopy (XPS). The DNA samples were irradiated for over 5 h and spectra were taken repeatedly every 30 min. In this approach the X-ray beam both damages and probes the samples. In most cases, XPS spectra have complex shapes due to contributions of C, N, and O atoms bonded at several different...
متن کاملRepair of soft X-ray damage to mammalian cell DNA.
[a-Z'P]ddATP ( I pCi) was added to cuvettes followed by 0.8 ml of cell suspension ( 1 0' cells). ( 0 ) after permeabilization cells were irradiated with I00 J m ? 248 nm light and the incubations quenched at the times shown by the addition of 0.5 ml o f 5 M-NaOH. ( m ) No 248 nm U.V. fact greatly increased the size of the initial peak of the incorporation of ['HITTP and [ "PITTP. It therefore s...
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Poly(ADP-ribose)polymerase-1 (PARP1) is a nuclear protein implicated in DNA repair, recombination, replication, and chromatin remodeling. The aim of this study was to evaluate possible differences between PARP1(-/-) and wild-type mice regarding induction and repair of DNA lesions in irradiated male germ cells. Comet assay was applied to detect DNA damage in testicular cells immediately, and two...
متن کاملStatic magnetic fields modulate X-ray-induced DNA damage in human glioblastoma primary cells
Although static magnetic fields (SMFs) are used extensively in the occupational and medical fields, few comprehensive studies have investigated their possible genotoxic effect and the findings are controversial. With the advent of magnetic resonance imaging-guided radiation therapy, the potential effects of SMFs on ionizing radiation (IR) have become increasingly important. In this study we foc...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2015
ISSN: 1664-8021
DOI: 10.3389/conf.fgene.2015.01.00062